It has been reported that ethyl ascorbic acid (INCI name is 3-o-ethyl ascorbic acid, 3OAA) is the best vitamin C derivative so far. 86404-04-8. PMID: 30311899. Product Introduction: Vitamin C ethyl ether, a Vitamin C that really can be absorbed by the skin. Excellent whitening effect: inhibits the activity of Tyrosinase by acting on Cu2+, and prevents the synthesis of melanin2%. Here, we examine the permeability of the HSE LabSkin TM to a model compound, 3-O-ethyl-l-ascorbic acid (EA) compared with human skin. SpecWhite VCE 3-O-ethyl ascorbic acid is an excellent choice for cosmetic chemists. Ethyl Ascorbic Acid, US $ 140 - 200 / Kilogram, 86404-04-8, 3-O-Ethyl Ascorbyl Ether, C8H12O6.Source from Hangzhou Lingeba Technology Co., Ltd. on Alibaba.com. That happens, too, making it ideal for use . Odor: characteristic. INCI name: 3-O-ETHYL ASCORBIC ACID. CAS No. 3-O Ethyl Ascorbic Acid Origin herbal Definition Ethyl ascorbic acid is a stable vitamin C derivative with excellent skin whitening effect INCI function skin caring, bleaching, Antioxidant Substance category No information available Characteristics Please log in to find out how this ingredient is characterized and may affect your health. Ethyl Ascorbic Acid have both an antioxidant and anti-inflammatory effect, and it's claimed to be able to boost the skin's collagen production. 3-O-ethyl ascorbic acid (3OAA) 3-O-ethyl ascorbic acid Ethylated vitamin derivative. On top of manufacturer claims, there is also clinical in-vivo (tested on real people) data showing that 2% EAC can improve skin tone and whiten the skin. It has a pretty short ingredient list, which doesn't seem to have any other beneficial ingredients besides the L-AA: Aqua (Water), 3-0 Ethyl Ascorbic Acid, Dipropyle-Ne Glycol, Peg-150, Phenoxyethanol, Sodium Citrate, Xantham Gum, Citric Acid, Chlorphenesin, Hydroxyethylcellulose, Disodium Edta. Ethyl ascorbic acid. Price: $36 for 0.5oz. Previously, we reported the effects of neat solvents on EA percutaneous absorption and observed that 0.6&ndash;7.5% of the applied EA was delivered through the skin over 24 h. In this work, we designed complex formulations using combinations of solvents that may act synergistically and . It provides its same benefits (brightening, collagen-boosting, and wrinkle prevention) with less irritation. 86404-04-8, Ethyl Ascorbic Acid is a stable derivative of ascorbic acid for used in skin lightening and anti aging products. $65.00. CAS-No. Side effects: It could irritate very sensitive skin. Its functions (INCI) Skin conditioning : Maintains skin in good condition. Including this potent ingredient is one of the best ways to cure hyperpigmentation. Sejauh ini ET-VC masih menjadi turunan asam askorbat paling baik. Previously, we reported the e ects of neat solvents on EA percutaneous absorption and observed that 0.6-7.5% of the applied EA was delivered through the skin over 24 h. Product Name: 3-O-Ethyl Ascorbic Acid: Batch Number: GW20191218A: Testing Regulation: Enterprise Standards: Package: Description. 130 Reviews. Repair skin cell activity and promote collagen production. Useful as water soluble antioxidant. to boost skin collagen synthesis. Fades hyperpigmentation. Ascorbic Acid and Sodium Ascorbyl Phosphate are two forms of Vitamin C that are used in skin care products aimed at boosting collagen synthesis and reversing signs of damage and aging in the skin. Products with 3-O Ethyl Ascorbic Acid -Ascorbic Acid in Skin Health Soledad Ravetti 1 , Camila Clemente 2 , Sofa Brignone 2 , Lisandro Hergert 2 , Daniel Allemandi 3 and Santiago . Ethyl ascorbic acid has an anti-inflammatory effect. 0 comments 100% Upvoted INCI Name 3-O-Ethyl Ascorbic Acid. Structure . Products. For this part of the experiment, Pinnell and his group applied a 15% ascorbic acid solution at pH 3.2 to pig skin for 5 days with a Hill Top Chamber. This lightweight serum contains 2 bioactive ingredients (DavosLife E3 Tocotrienols and Vitamin C). Hence, you get durability and effectiveness in one product! Ethyl Ascorbic Acid ( 3-O-ethyl ascorbic acid) can also reduce melanin pigment. China 3-O-Ethyl-L-Ascorbic Acid CAS: 86404-04-8 Cosmetic Raw Material for Skin Care, Find details about China Pharmaceutical Chemical, Additive from 3-O-Ethyl-L-Ascorbic Acid CAS: 86404-04-8 Cosmetic Raw Material for Skin Care - Ningbo Newrainbow Biochemicals Co., Ltd. Inhibition of melanogenesis (melanin production) results in a skin lightening effect at higher concentrations of ethyl ascorbic acid. 3-O-Ethyl-L-ascorbic acid, also call Vitamin C Ethyl Ether, it is a Vitamin C That Really Can Be Absorbed By The Skin. it basically increases the amount of time it takes for your skin to turn red underneath the sun, when used in conjunction with sunscreen, especially so if sunscreen lets say is spf 30 and it takes you 30 times the amount of time you usually take to burn right by using spf 30, adding vitamin c is going to even increase that time to longer so Face moisturizing serum (3.41%) Day anti-ageing face serum (2.37%) What it is: A water-soluble derivative of Vitamin C. What it does: It's very stable and easily converts to L-Ascorbic Acid when applied to the skin. The barrier function of such models however, is normally less developed than human skin. Here, the anti-melanogenic activity of EAA was demonstrated through Nrf2-mediated -MSH inhibition in UVA-irradiated keratinocytes (HaCaT) and . Abstract: 3-O-ethyl l-ascorbic acid (EA), an ether derivative of Vitamin C, is widely used in skincare formulations. Victoria-Martnez, Ana M. MD; Mercader-Garca, Pedro MD. The compound 3-o-ethyl-l-ascorbic acid (EA) has been developed as a stable vitamin C derivative and has been used in topical products. Ethyl Ascorbic Acid is water and oil soluble and should be used in concentrations between 0.5% and 3%. The compound 3-o-ethyl-l-ascorbic acid (EAA) has been further developed by Sokrpe Laboratories as a stable vitamin C derivative and is being used in a topical product we branded Super Boost. (Skin penetration) L-Ascorbic Acid (LAA) Sodium Ascorbyl Phosphate (SAP) Ascorbic Acid 2-Glucoside (AA2G) . . It is fat-soluble as opposed to water-soluble (like ascorbic acid, sodium ascorbyl phosphate and magnesium ascorbyl phosphate). Ethyl ascorbic acid is L-ascorbic acid (scientific name of vitamin C) with an ethyl group derivative, present on its third carbon. Ethyl ascorbic acid. Studies reveal that Ethyl Ascorbic Acid helps in stopping the . Get Latest Price Request a quote Thirthraj Consolidated Company Chamrajpet, Bengaluru, Karnataka 3.8 /5 (88) GST- 29ABVPS3711J1ZZ This ingredient is present in 0.21% of cosmetics. Amounts up to 30% have been shown to be non-irritating on human skin samples. Ethyl Ascorbic Acid application cases in major cosmetic brands in the world: 3-0-Ethyl Ascorbic Acid shows very good stability due to its unique chemical structure, because the ethyl group . Overall, magnesium ascorbyl phosphate appears to be a good choice for people with sensitive skin. Both have their advantages and disadvantages when it comes to stability, cost, and effectiveness. The aims of this work were to conduct a comprehensive. MF C 8 H 12 O 6. With this kind of effectiveness, you can see why I insisted these next generation "C's" form the foundation of the Systme 41 Vitamin C Serum. Neutralization with sodium bicarbonate and addition of ethyl acetate to extract and crystallize to obtain 8.2g of 3-O-ethyl ascorbic acid with a . 3-0 Ethyl Ascorbic Acid, For Used In Cosmetics 1,500/ Kg Get Latest Price Skin lightening agent that evens out skin tone View Complete Details Fill the quantity to get latest price! It should also be suitable for the skin and it is. Plus, both ethyl ascorbic acid and BV-OSC are highly stable and don't lose their potencyeven if they sit on the shelf for months. In contrast to free AA, Ethyl Ascorbic Acid freely penetrates into skin, where it is further metabolized to Ascorbic Acid, ensuring a remarkable higher bioavailability and a consequent higher concentration in deeper skin target sites. Due to its stability, lesser amounts are needed compared with pure vitamin C. Levels above 5% may also be used, depending on desired benefits. Allergic Contact Dermatitis to 3-o-Ethyl- l -Ascorbic Acid in Skin-lightening Cosmetics. Purchase monohydrate 3 o ethyl ascorbic acid at Alibaba.com. Sehingga efeknya lebih baik daripada asam askorbat murni. It has a much greater skin penetration rate, highly effective in antioxidant and antiaging skin care without skin irritation. Just remember that after Vitamin C, it's best . With the reduction of Tyrosinase, which results in a reduction in the formation of melanin pigment. For instance, the 3-O-Ethyl-L-ascorbic Acid serum enhances your skin firmness, thus fading the stubborn wrinkles and fine lines.That makes this drug one of the best anti-aging supplements on the . Products; Suppliers; fishing rod glove-fine mesh wire cloth-coin operated locker locks-ws c3750g 12s s-2kg co2 extinguisher- . This structural modification protects the 3-OH group from ionization, and thus the molecule from oxidation, but also results in changes in the physicochemical properties. concentrated 3-O-ethyl ascorbic acid at 30% in combination with lactic acid at 1%, to contrast the effect of skin ageing and irregular pigmentation due to the normal physiological decline of the skin on both in vitro cell cultures and 3D reconstructed tissue models. Materials and Methods 2.1. International Nomenclature of Cosmetic . Methods: Skin uptake and permeation of EA was investigated in vitro using heat-separated human epidermis and LabSkin TM. This ethyl derivative makes L-ascorbic acid (AA) soluble and stable in both oil and water. Best & most potent Vitamin C formula made with pure Ethyl Ascorbic Acid. But vitamin C itself is easy to oxidise and easily decomposed in the water phase. Improves the complexion, and enhances skin elasticity. Manufacturers suggested Usage : 0.01 to 2.0%. The strong point of EAC though is skin brightening. In a nutshell, an excessive amount of melanin present in your body can lead to the development of hyperpigmentation. Dikarenakan struktur kimianya yang sangat stabil, kandugan ini dapat masuk ke dalam kulit dan dimetabolisme oleh tubuh sebagai asam askorbat. This chemical variation makes ethyl ascorbic acid a highly stable vitamin C derivative, soluble in water and oil. Ethyl Ascorbic Acid, INCI: 3-0-ethyl ascorbic acid. 3-O-ETHYL ETHER L-ASCORBIC ACID, ETHYL ASCORBIC ACID, and L-ASCORBIC ACID, 3-O-ETHYL ETHER Common concerns See how this product scores for common concerns. Increased collagen production twice as much as ascorbic acid. 3-O-Ethyl-L-Ascorbic Acid is a lipophilic derivative of a water-soluble vitamin C, not only in the formulation to be very convenient to use and more easily penetrate it into the dermal layer of the stratum corneum, into the skin easily decomposed by enzymes play a role of vitamin C, thereby increasing its bioavailability, and ordinary vitamin C is difficult to be absorbed through skin . Skin whitening/brightening effects. Ethyl ascorbic acid or 3-O-Ethyl-L-Ascorbic acid (86404-04-8) is a molecule that is produced by modifying the ascorbic acid, mostly known as Vitamin C. The modification is usually done to improve the molecule's stability as well as enhancing its transportation through the skin and as a pure Vitamin C, it's easily degraded. Krishana Enterprises is a leading supplier of 3-O-Ethyl Ascorbic Acid (Vitamin C Derivative), which can be used as one of the most stable ingredients and Vitamin C derivatives for whitening, brightening and anti-aging skin care products and the medical products that prevent and relieve the fatigue and inflammation of muscles and joints.Ethyl . Certainly, 3-O-ethyl-L-ascorbic acid takes things further and improves the molecules' stability and its transportation efficacy to the skin, being absorbed faster and better. 3 o ethyl ascorbic acid can also promote wound healing. Ethyl ascorbic acid (EAA) is the newest form of vitamin C with the highest bio-availability among all vitamin C derivatives. It can penetrate the skin better and faster, without irritation. In addition, when topically applied it is thought to help heal acne, increase the barrier function of skin to decrease moisture loss, protect from UV radiation, and prevent age spots. 3.. May be a great option to those that have sensitive skin.-3-O Ethyl Ascorbic Acid- a derivative of vitamin c that is a water-soluble formula that is known for being stable and easily absorbed. Cosmetic Peptides Whitening . Brightening serum. It is not only chemically stable, but it is easily decomposed by biological enzymes after entering the skin to play the role of vitamin C. In addition, ethyl ascorbic acid has a lipophilic and hydrophilic . 3-O-ethyl ascorbic acid (EAA) is an ether-derivative of ascorbic acid, known to inhibit tyrosinase activity, and is widely used in skincare formulations.Nevertheless, the molecular mechanisms underlying the EAA's effects are poorly understood. The strong point of EAC though is skin brightening. Country/Region: china: Company: Green Stone Swiss Co ., ltd: Categories: Polyacrylic Acid Sodium Salt: Telephone These benefits make Ascorbic Acid an extremely attractive skincare ingredient, both for those who are trying to correct for damage and signs of aging and for those using it as a preventative measure. Usage levels of 3-O ethyl ascorbic acid in skin care typically fall between 0.5-5%. Ascorbyl palmitate (AA-PAL or sometimes AP) is a vitamin C ester (formed from ascorbic acid and palmitic acid). Ethyl Ascorbic Acid merupakan turunan ethered asam askorbat. 1. LOW Cancer LOW Allergies & Immunotoxicity LOW Developmental and Reproductive Toxicity LOW Use Restrictions Ingredient concerns CONCERNS DATA SOURCES Products with this Ingredient Data gaps It's worth a try, especially if you are after . 3-O-ethyl-l-ascorbic acid (EA) is an l-ascorbic acid derivative with an ethyl group at the third carbon position. Made with 15 % Vitamin C (3-0-ethyl ascorbic acid) and Vitamin E and Kojic acid. 3. This is for cosmetic use only. . From the experiment it was found that Ethyl Ascorbic Acid ( 3-O-ethyl ascorbic acid) Has a brightening effect on the skin. Previously, we reported the effects of neat solvents on EA percutaneous absorption and observed that 0.6-7.5% of the applied EA was delivered through the skin over 24 h. However, this is not enough to use this ingredient in skincare. Brightening skin, preventing and healing oxidative damage, and boosting collagen production is a major "youthful appearance" trifecta. A formulation by KLK OLEO. Chemically, 3-O-Ethyl ascorbic acid protects the skin from oxidative stress by sequentially donating electrons to neutralize the free radicals. Converts into ascorbic acid when applied to skin More stable than ascorbic acid May penetrate the skin faster than other forms of vitamin C Oil-soluble vitamin C derivative Converts into ascorbic acid when applied to skin Stable at pH < 5 May penetrate the skin better than other forms of vitamin C Ethylated form of vitamin C 3-o-ethyl-ascorbic-acid products Find 3-o-ethyl-ascorbic-acid products, manufacturers, suppliers and exporters . It has effect of whitening skin. Vitamin C Serum with 10% Ethyl Ascorbic Acid. At a pH of ~4.0 it is highly stable and effective; Contains 1% Acetyl Glucosamine (AG), an amino . 1. dissolves in both oil base and water base. Author Information. One of the strong point Ethyl Ascorbic Acid has, is its ability to improve skin tone and brighten the skin. Additionally, it is less irritating to the skin. 25ml / 0.84 fl oz. Magnesium ascorbyl phosphate is a water-soluble derivative of vitamin C. It is nonirritating and has a conversion percentage to L-ascorbic acid of over 60%, enough. A lightweight daily serum formulated with 10% Vitamin C (Ethyl Ascorbic Acid) alongside Hyaluronic Acid to give dull complexions a boost. Effective Whitening And Freckle-Removing, Repair Skin Cell Activity, Promote The Production Of Collagen. 3-O-Ethyl-L-ascorbic acid 99.0% (CAS 86404-04-8) . EAC seems to have both an antioxidant and anti-inflammatory effect, and it's claimed to be able to boost the skin's collagen production. Views : 1. Home. Or 4 payments of $16.25 with or. 2. China Cosmetic Ingredient Ethyl Ascorbic Acid CAS 86404-04-8 3-O-Ethyl-L-Ascorbic Acid Skin Whitening Cosmetics, Find details about China Ethyl Ascorbic Acid, Ethyl Ascorbic Acid from China Cosmetic Ingredient Ethyl Ascorbic Acid CAS 86404-04-8 3-O-Ethyl-L-Ascorbic Acid Skin Whitening Cosmetics - Tianjin YR Chemspec Technology Co., Ltd. 10g of 3-O-ethyl-5, 6-O-isopropylidene ascorbic acid is dissolved in 100 ml of methanol, then 5 ml (volume fraction 50%) hydrochloric acid is added, and the reaction is heated to 60 for 3 hours. Improve skin dullness and give skin elasticity; 4. MW 204.18. Actives 3-O-Ethyl Ascorbic Acid: A Stable, Vitamin C-Derived Agent for Skin Whitening Sep 27th, 2013 Jill Hsu, Corum Inc. A flawless complexion is without doubt a desirable attribute across many cultures. Ethyl ascorbic acid . 2 . Use: Ethyl Ascorbic Acid is a stable Vitamin C derivative with excellent skin brightening activity. Highly stablized and effective Vitamin C serum for brighter & illuminating skin. In these experiments, the ascorbic acid solution was applied with a Hill Top Chamber, which occludes the skin, reducing evaporation and theoretically enhancing skin penetration. 3-O-Ethyl-Ascorbic Acid and Emollients You can use ethyl-L-ascorbic acid day and night after the cleansing step of your skincare routine. Super Boost - does not only provide superb whitening effects, but also serves as a potent anti-aging active that boosts collagen synthesis and . Update time : 2022-09-15 17:19:52. The suggested pH is between 3.0-6.0. It can be metabolized in the same way as vitamin C in human body after entering skin, which enables it to play a better effect of Vitamin C. . When pH value of Ethyl Ascorbic Acid is 3.0-6.0, the whitening and freckling effect is the best. That is much higher than 40-50% content present in other Vitamin C derivatives. Top 5 benefits of Ethyl Ascorbic Acid For Skin. About us. Specifications . Ethyl ascorbic acid is what maybe considered a . 3-O-ethyl l-ascorbic acid (EA), an ether derivative of Vitamin C, is widely used in skincare formulations. Cosmetic Raw Materials. Improves the appearance of pigmentation, tone, texture. On top of manufacturer claims, there is also clinical in-vivo (tested on real people) data showing that 2% EAC can improve skin tone and whiten the skin. Get a full range of quality 3 o ethyl ascorbic acid at the best deals at low prices and unbelievable discounts. Inquiry Basket(0) Help; Products. It is formulated to protect skin from oxidative stress and inflammation, brighten skin and delay premature skin aging to promote healthy, radiant-looking skin. In a 1% aqueous solution, the pH should be 3.5-5.5. It is known to play a role in collagen production. Additionally, Ethyl Ascorbic Acid has strong antibacterial and anti-inflammatory effect. It is used to provide skin lightening, support collagen production, provide UV protection, reduce visible signs of aging, among other things. Anallerg VCE is 99% 3-0-Ethyl Ascorbic Acid, which is a derivative modified from vitamin C. 3-0-Ethyl Ascorbic Acid is an excellent whitening active ingredient with anti-oxidation, anti-wrinkle and anti-wrinkle effects. l. -Ascorbic Acid in Skin-lightening Cosmetics. 2018 Jul/Aug;69(4):233-243. Repairs skin cells, and accelerates the synthesis of collagen. Functions . It can resist inflammation caused by sunlight. Antioxidant Ability and Stability Studies of 3-O-Ethyl Ascorbic Acid, a Cosmetic Tyrosinase Inhibitor.